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Peto's paradox : ウィキペディア英語版
Peto's paradox
Peto's Paradox is the observation, due to Richard Peto, that at the species level, the incidence of cancer does not appear to correlate with the number of cells in an organism. For example, the incidence of cancer in humans is much higher than the incidence of cancer in whales. This is despite the fact that a whale has many more cells than a human. If the probability of carcinogenesis were constant across cells, one would expect whales to have a higher incidence of cancer than humans.
==Original formulation==
Peto, a statistical epidemiologist at the University of Oxford, first formulated the paradox in 1977.〔〕 Writing an overview of the multistage model of cancer, Peto noted that, on a cell-for-cell basis, humans were much less susceptible to cancer than mice:
Peto went on to suggest that evolutionary considerations were likely responsible for varying per-cell carcinogenesis rates across species.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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